尹建華

作者: 訪問量:2246發布時間:2018-09-06


姓名:尹建華性別:職務:
職稱:教授導師類別:博士生導師辦公室:
研究領域:生物醫學光譜學及成像(Biomed Spectroscopy and Micro-Imaging)
光譜顯微圖像分析(Spectroscopic Image Analysis)
計量學建模及計算(Chemometrics Modeling and Assessment)
生醫光子學技術開發及應用 (D&A of Biomed Photonics Tech.)
光譜生物分析化學(Spectroscopic Bioanalytical Chemistry)
藥物及腫瘤的光譜學檢測 (Spectroscopic detection of Drug and Tumor)
電話:
Email:yin at nuaa.edu.cn
個人簡介

南京航空航天大學生物醫學工程係教授,中國光學學會生物醫學光子學專業委員會委員,中國生物醫學工程學會納米醫學分會、中國電子學會生命電子學分會、日本分析化學學會等學會高級會員。發表文章七十餘篇,一作及通訊作者SCI論文三十多篇。申請發明專利3項,已授權1項。主持NSFC麵上項目、教育部博士學科點基金、江蘇省自然科學基金和江蘇省“六大人才高峰”高層次人才計劃等項目。作為項目主要完成人參與完成2項美國NIH R01項目,2項日本文部省重大項目,3項國家自然科學基金麵上項目。

指導江蘇省優秀學術碩士學位論文1項(2017),研究生創新基金項目、校優秀碩士學位論文、校優秀本科畢業設計各2項。指導研究生獲得研究生國家獎學金(2015、2016年度3人各20K)、中航工業獎學金(2017年度1人6K)、南京市第十二屆自然科學優秀學術論文三等獎。


學術成果

部分代表性成果:[to update soon or to visit http://bmsi.nuaa.edu.cn/]

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【紅外光譜成像/分析&化學計量學&熒光成像光譜&光子技術@生物醫學&生物醫學光子學】

[1] Zhi-Hua Mao, Jian-Hua Yin*, Xue-Xi Zhang, Xiao Wang, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilage by Fourier transform infrared imaging and Fisher’s discriminant analysis, Biomed. Opt. Express, 7(2) 448-453, 2016(SCI IF3.648)

[2] Zhi-Hua Mao †, Yue-Chao Wu †, Xue-Xi Zhang, Hao Gao and Jian-Hua Yin*, Comparative study on identication of healthy and osteoarthritic articular cartilages by fourier transform infrared imaging and chemometrics methods, J Innov Opt Health Sci, 10, 1650054, 2017 (SCI)

[3] Xue-Xi Zhang, Jian-Hua Yin*, Zhi-Hua Mao, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilages by Fourier transform infrared imaging and partial least squares-discriminant analysis, J Biomed Opt, 20(6), 060501, 2015(SCI IF2.85)

[4] Xue-Xi Zhang, Zhi-Hua Mao, Jian-Hua Yin*, Yang Xia, Determination of collagen and proteoglycan concentration in osteoarthritic and healthy articular cartilage by Fourier transform infrared imaging and partial least square, Vib Spectrosc., 78, 49-53, 2015(SCI IF2.1)

[5] Zhi-Hua MAO, Xue-Xi ZHANG, Yue-Chao WU, Jian-Hua YIN*, XIA Yang, Fourier Transform Infrared Microscopic Imaging and Fisher Discriminant Analysis for Identification of Healthy and Degenerated Articular Cartilage, Chin J Anal Chem, 43, 518-522, 2015(SCI)(EN)

毛之華, 張學喜, 吳曰超,尹建華*,Xia Yang, 健康和病變關節軟骨的傅裏葉變換紅外光譜顯微成像及Fisher判別. 分析化學, 43: 518-522, 2015 (SCI) (CN)

[6] Jian-Hua Yin, Yang Xia*, "Proteoglycan Concentrations in Healthy and Diseased Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression", Spectrochim Acta A: Molecular and Biomolecular Spectroscopy, 133, 825-830, 2014 (SCI, IF=2.653)

[7] Xue-Xi Zhang, Zhi-Yan Xiao, Jian-Hua Yin*, et al. Concentration Determination of Collagen and Proteoglycan in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and PLS, Proc. of SPIE, 9230: 923015-1~7, 2014 (EI)

[8] 吳曰超, 張學喜, 毛之華, 尹建華*. 關節軟骨內膠原纖維各向異性的紅外光譜學顯微成像研究, 光譜學與光譜分析, 36(7): 2071-2075, 2016 (SCI)

[9] 尹建華*,黃鳳玲,錢誌餘,謝捷如,傅裏葉變換紅外光譜學顯微成像技術在骨病研究中的應用和進展,光譜學與光譜分析, 34, 340-343, 2014 (SCI)

[10] 王瀟,吳曰超,何俊豪,毛之華,張學喜,蔡金洋,王強,尹建華*, 關節軟骨的熒光顯微檢測方法研究, 光散射學報, 28(2), 185-189, 2016

[11] 毛之華,尹建華*, 基於主成分分析的不同預處理方法對關節軟骨分類的影響, 光散射學報, 28(3), 264-269, 2016

[12] 吳曰超, 尹建華*, 劉玉, 毛之華, 關節軟骨紅外光譜成像及分析方法研究,南京航空航天大學學報, 47, 421-427, 2015 (EI)

[13] 尹建華,關節軟骨和骨關節炎的傅裏葉變換紅外光譜學顯微成像研究進展,科學通報, 59 (27) ,2645 – 2651, 2014 (重核)

[14] 尹建華,關節軟骨主成分的紅外光譜學分析及表征,光散射學報,26(2),213-218, 2014

[15] 尚林偉,尹建華*,軟骨退變的顯微熒光光譜研究,中國科技論文,11(24),2811-2815,2016


[16] Z. Xiao, J.H. Yin*, “Spectroscopic studies on bilirubin aggregate at liquid/liquid interface”, Anal. Bioanal. Chem., 405, 2723-2728, 2013 (SCI, IF=3.778)

[17] J.H. Yin*, Y. Xia, “Comparison of macromolecular component distributions in osteoarthritic and healthy cartilages by Fourier transform infrared imaging”, J Innov. Opt. Health Sci., 6, 1350048, 2013 (SCI)

[18] J.H. YIN, Y. Xia*, “Concentration Profiles of Collagen and Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Spectrochim. Acta A, 88, 90-96, 2012 (SCI, IF=2.663)

[19] J.H. YIN, Y. Xia*, “Chemical Visualization of Individual Chondrocytes in Articular Cartilage by Attenuated-Total-Reflection Fourier Transform Infrared Microimaging”, Biomed. Opt. Express, 2, 937-945, 2011 (SCI, IF=3.648)

[20] J.H. YIN, Y. Xia*, “Depth-dependent Anisotropy of Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging”, Vib. Spectrosc., 57, 338-341, 2011 (SCI, IF=2.083)

[21] J.H. YIN, Y. Xia*, “Macromolecular Concentrations in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Appl. Spectrosc., 64, 1199-1208, 2010 (SCI, IF=1.663)

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【共焦顯微拉曼&圓二色譜&熒光光譜&界麵分子聚集@生物分析化學】

[22] J.H. Yin, H. Watarai*, “Effect of Chloroform on Complexation and Chiral Aggregation of Bilirubin–Bovine Serum Albumin at Heptane/Water Interface”, J. Colloid Interface Sci., 329, 325-330, 2009 (SCI, IF=3.263)

[23] D. Tokunaga, H. Takechi, J.H. Yin, H. Watarai*, T. Ohde, “Microscopic Observation of Second Harmonic Generation from Chiral Surfaces”, Anal. Sci., 25, 311-314, 2009 (SCI, IF=1.255)

[24] J.H. Yin, H. Watarai*, “Chiral Complexation and Aggregation of Bilirubin with Serum Albumin at Liquid/Liquid Interface”, Anal. Bioanal. Chem., 389, 895-902, 2007 (SCI, IF=3.778)

[25] J.H. Yin, H. Watarai*, “Resonance Raman Spectroscopic Study on Chiral Aggregation of Bilirubin-Bovine Serum Albumin Complex Formed at Liquid/Liquid Interface”, Anal. Sci., 23 841-846, 2007 (SCI, IF=1.255)

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【光纖Raman光譜@分子光譜學&光學光子學】

[26] J.H. Yin*, Z.Y. Xiao, Z.W. Li, “Ultralow concentration beta-carotene molecule detection by liquid-core optical fiber resonance Raman spectroscopy”, Vib. Spectrosc., 62, 7-9, 2012 (SCI, IF=2.083)

[27] J.H. Yin, Z.W. Li*, “Resonance Raman Spectra of n-pi* Singlet–triplet Transition of p- benzoquinone at Low Concentrations”, Spectrochim. Acta Part A, 61, 495–498, 2005 (SCI, IF=2.098)

[28] J.H. Yin, Z.W. Li*, Y.J. Tian, Z.W. Sun, X.L. Song, “A Study on Raman Scattering Cross Section of Carbon Tetrachloride at low Concentrations”, Appl. Phys. B: Lasers and Optics, 80, 573-576, 2005 (SCI, IF=2.189)

[29] J.H. Yin, Z.W. Li*, C.N. Ren, L.Y. Zhang, “Visible Absorption Spectra of n-pi* Singlet-Triplet Transition of p-benzoquinone in CS2 and its Resonance Raman Spectra”, Spectrosc. Spect. Anal., 25, 1821-1823, 2005 (SCI)

[30] J.H. Yin, S.Q. Gao, Z.W. Li*, Y.N. Yu, G.H. Lu, Y.J. Tian, “Effect of Solution Concentration on Raman Scattering Cross Section of Carbon Tetrachloride”, J. Raman Spectrosc., 35, 1042-1046, 2004 (SCI, IF=3.087)

[31] J.H. Yin, S.Q. Gao, X.F. Xu, Z.W. Li*, “Experimental Studies on Effect of Concentration of CS2 on Linewidth and Frequency Shift of Raman Spectrum”, Chem. J. Chin. Univ., 23, 2300- 2302, 2002 (SCI)














































承擔項目

主持項目:

1. 2016 江蘇省第十三批“六大人才高峰”高層次人才計劃項目

2. 國家自然科學基金麵上項目 ( 61378087)

3. 高等學校博士學科點專項科研基金 (20133218120017)

4. 江蘇省自然基金 (BK20151478)

5. 南京航空航天大學引進人才啟動基金 (1003-56YAH13005)


參研項目:

   2 項美國NIH R01項目 2008-2012

   2 項日本文部省重大項目 2005-2008

   3 項國家自然科學基金 2000-2005


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